KMID : 1094020170340040299
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Journal of Veterinary Clinics 2017 Volume.34 No. 4 p.299 ~ p.303
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Stereotactic Body Radiation Therapy in Canine Nasal Transitional Cell Carcinoma
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Park Noh-Won
Lee Dong-Han Huh Ra-Young Han Jae-Woong Eom Ki-Dong
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Abstract
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An 11-year-old neutered male Maltese presented for radiation therapy for nasal transitional cell carcinoma. Stereotactic body radiation therapy (SBRT) was provided for the owner¡¯s request. Clinical signs improved 6 days after radiation therapy. Adverse effects including alopecia and pigmentation on the facial region were observed at 21 days after radiation therapy. The first follow-up computed tomography (CT) 96 days after SBRT revealed that the nasal tumor had decreased by 60.63% compared with the pre-treatment volume. Clinical signs related with the tumor reassigned 151 days after SBRT, and the second follow-up CT revealed tumor relapse. The patient was died 238 days after SBRT due to tumor relapse. SBRT showed a good tumor control effect with relatively mild radiation toxicity relative to other radiation therapy modalities, in accordance with a previous study. Further studies are needed to establish an effective treatment protocol, such as total dose, fractional dose, and inter-fractional period, in canine malignant nasal tumors.
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KEYWORD
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nasal tumor, stereotactic body radiation therapy, dog
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